INVESTORS

The Company is backed by experienced and committed healthcare investors:

Care Capital is a life sciences venture capital firm based in Princeton, New Jersey. Care Capital invests in entrepreneurial companies that are developing pre-clinical or early clinical pharmaceutical assets and currently manages approximately $500 Million in capital, with investment experience that spans all therapeutic areas. Care Capital has made investments in both private and public opportunities in both the United States and Europe.

Investor Growth Capital

A subsidiary of Investor AB, Investor Growth Capital (IGC) U.S. was launched in 1995. IGC focuses upon the Healthcare and Information Technology sectors within North America. Within the Healthcare segment, their industry sector focus is medical devices and pharmaceuticals. IGC U.S. has invested $1.5 Billion in over 100 companies.

ProQuest Investments

Founded in 1998, ProQuest is a healthcare venture capital firm with over $875 million under management. With over 40 investments in such diverse therapeutic categories as oncology, pain and infectious disease, ProQuest Investments seeks to build long term, mutually beneficial partnerships with outstanding entrepreneurs.

Kaiser Permanente Ventures

Kaiser Permanente Ventures, the corporate venture arm of Kaiser Permanente (KP), is dedicated to forming effective partnerships with innovative companies. KP Venture investments are designed to improve quality, service, and affordability for KP members, introduce innovative products and services to the KP organization, and generate attractive rates of return. KP Ventures invests in medical devices, health care services, and health care information technology companies.

Novitas Capital (formerly PA Early Stage Partners)

Founded in 1997, Novitas Capital mines innovation and opportunities
where investment for seed, start-up and early stage technology and life sciences ventures is scarce. Novitas discovers companies at their earliest stages, thoroughly assesses the opportunity and, typically leads investment rounds taking an active role in facilitating their success. Based in
Wayne, Pennsylvania, with offices in Pittsburgh, Pennsylvania; Allendale, New Jersey; and Morgantown, West Virginia, Novitas currently has approximately 30 active portfolio companies and $237.5 million under management across three venture capital funds.