Patented technology
The Company’s technology utilizes passive enhancement chemistry in a patented, dual
delivery system for the use of estrogen and progestin in contraception.
Active Adhesive System designed to deliver estrogen and progestin combination over the 7-day
period at doses needed for contraception.
  U.S. 7,045,145
  Intermediate wet formulation (manufacturing patent)
  U.S. 7,384,650
  Dry formulation – provides ranges for four active enhancers used to deliver estrogen and
progestin for contraception
  (Patent pending)
  PK claims (CMAX and AUC) for ethinyl estradiol and levonorgestrel
  System claims with expanded scope
  Unique 7-day/3-week delivery curve
Peripheral Adhesive System prevents evaporation, maintains stability and improves adhesion and
comfort
  (Patent pending)
  Peripheral adhesive and release liner to prevent evaporation of substances and maintain product
stability
  (Patent pending)
  Alternative design using ultrasonic welding of backing layer to release liner to prevent
evaporation of substances
Unique transdermal dosing regimens for next generation products
Reflects patient preference on controlling frequency/duration of menses and the benefits of
shortened hormonal free intervals
Applications to other therapeutic areas and substances
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